College of Medicine Pochon Cha University Industry
发明人:
MOON, Ji-Sook,LEE, Hyun-Seob,SHIN, Yeon-Ho
申请号:
EP14903548
公开号:
EP3205717A4
申请日:
2014.10.10
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention provides a method for proliferating neural progenitor cells and a composition for treating neurological diseases, the composition including a proliferated neural progenitor cell. When a fetal neural progenitor cell is cultured under a hypoxia condition and/or in a medium containing tocoperol, tocoperol acetate, or a mixture thereof, the improved cell proliferation rates of the fetal neural progenitor cell are confirmed. In addition, considering an effect of the neural progenitor cell on preventing differentiation thereof into neurons at the time of proliferation, the present disclosure may contribute to mass production of neural stem cells, and accordingly, the proliferated neural progenitor cell is expected to be utilized in the treatment of a neurological disease.