The National Institute for Biotechnology in the Negev Ltd.
发明人:
Varda Shoshan-Barmatz,Arie Lev Gruzman
申请号：
US15700801
公开号：
US10434099B2
申请日:
2017.09.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to use of small organic compounds interacting with the Voltage-Dependent Anion Channel (VDAC) for the treatment of diseases associated with central nervous system (CNS) disorders, including psychotic disorders, mood disorders, neurodegenerative diseases. In particular the present invention relates to the use of substituted piperazine- and piperidine-derivatives and pharmaceutical compositions comprising same for the treatment of psychotic disorders including schizophrenia, mood disorders, and neurodegenerative diseases.
