Broeckx, Rudy Laurent Maria,Filliers, Walter Ferdinand Maria,Nieste, Patrick Hubert J.,Copmans, Alex Herman,Vanhoutte, Filip Marcel C.,Leys, Carina
申请号：
AU2013234080
公开号：
AU2013234080B2
申请日:
2013.03.13
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
There is provided inter alia a dry powder pharmaceutical formulation for inhalation comprising: (i) 6-(2-((4-amino-3-(3-hydroxyphenyl)-1 H-pyrazolo[3,4-d]pyrimidin-1-yl) methyl)-3- (2-chlorobenzyl)-4-oxo-3,4-dihydroquinazolin-5-yl)-N, N-bis(2-methoxyethyl)hex-5- ynamide or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof and solvates thereof in particulate form as active ingredient； (ii) particulate lactose as carrier； and (iii) a particulate stabilizing agent selected from metal salts of stearic acid such as magnesium stearate and metal salts of stearyl fumarate.
