Rudy Laurent Maria Broeckx,Walter Ferdinand Maria Filliers,Patrick Hubert J. Nieste,Alex Herman Copmans,Filip Marcel C. Vanhoutte,Carina Leys
申请号：
US14381273
公开号：
US20150099768A1
申请日:
2013.03.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
There is provided inter alia a dry powder pharmaceutical formulation for inhalation comprising: (i) 6-(2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl) methyl)-3-(2-chlorobenzyl)-4-oxo-3,4-dihydroquinazolin-5-yl)-N,N-bis(2-methoxyethyl)hex-5-ynamide or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof and solvates thereof in particulate form as active ingredient； (ii) particulate lactose as carrier； and (iii) a particulate stabilizing agent selected from metal salts of stearic acid such as magnesium stearate and metal salts of stearyl fumarate.
