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Pyridin-2-one compounds and their use as modulators of the dopamine D3 receptor
专利权人:
Hervé Geneste;Andreas Haupt;Wilfried Braje
发明人:
Hervé Geneste,Wilfried Braje,Andreas Haupt
申请号:
US13103734
公开号:
US08334289B2
申请日:
2011.05.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to novel pyridin-2-one compounds of general formula (I), in which A represents a 4- to 6-membered hydrocarbon chain that can have 1 or 2 methyl groups as substituents, wherein 1 or 2 carbon atoms can be replaced by oxygen, a carbonyl group or sulfur, and the hydrocarbon chain can have a double bond or a triple bond; R1, R2, R3 and R4 have the meanings as cited in the claims and in the description. The invention also relates to the tautomers of compounds I, the physiologically acceptable salts of compounds I, and to the physiologically acceptable salts of the tautomers of compounds I. The invention also relates to the use of compounds of general formula (I) and of the tautomers, and to the use of the physiologically acceptable salts of compounds I and of the tautomers for producing a pharmaceutical agent for treating diseases that respond to the influence of dopamine D3 receptor antagonists or agonists.
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