Design and development of an affordable, user-friendly, and portable POCT hand tremor detection device has been reported. This device is composed of a detection unit, a flexible pressure sensor, a signal processing unit, and a power supply. The detection unit is composed of the sensor and press-knob. The flexible pressure sensor is a combination of usually spaced apart flexible polymer preferably polydimethylsiloxane, flexible substrate preferably paper, and a conductive coating preferably reduced graphene oxide (RGO). When the users put pressure on the press-knob through the fingers, the flexible pressure sensor actuates and bends so that conductive RGO layers on the flexible substrates come in contact with each other to generate an output current. The electrical circuits in the signal processing unit are laid down in such a manner that the magnitude of this output current varies with the tremor between the fingers, which eventually converted into an electrical signal showing the variation in the hand tremor with time. The proposed POCT device is wirelessly connected to an android mobile application to measure the hand tremors for a longer period of time, display on the mobile interface, and store the data for future analysis of the neurological disorders. The proposed POCT device has the capability to detect the neurological disorders at the mature as well as at the early stages with the vision of control and prevention of these diseases.Conception et le développement d'un dispositif de détection de point d'intervention lors de tremblement de main portable et abordable. Ce dispositif est composé d'une unité de détection, d'un capteur de pression flexible, d'une unité de traitement de signal et d'une alimentation électrique. L'unité de détection est composée du capteur et du bouton de pression. Le capteur de pression flexible est une combinaison de polymères souples généralement espacés, de préférence du polydiméthylsiloxane, du substrat souple de préférence du pap