A 13-DEOXY ANTHRACYCLINE AND A TAXANE CAN BE ADMINISTERED TO A PATIENT SIMULTANEOUSLY, SEPARATELY, SEQUENTIALLY, OR CONSECUTIVELY TO PRODUCE A THERAPEUTIC ANTICANCER EFFECT WITH REDUCED TOXICITY AND SIDE EFFECT PROFILE, COMPARED TO THE ADMINISTRATION OF EQUIEFFECTIVE AMOUNTS OF EITHER COMPOUND ALONE. A COMPOSITION OR PREPARATION OF A 13-DEOXY ANTHRACYCLINES AND A TAXANE FOR PRODUCING A POTENT ANTICANCER THERAPEUTIC EFFECT IS ALSO PROVIDED.