The drug components of the compound can be used in autoimmune diseases, flammability disorders, cancer, non malignant diffusion disorders and other diseases related to Btk. 1. Claim 1: a formula compound (1),a. A plasma or a pharmaceutically acceptable compound salt, or a Dow, wherein: R1 is selected from hydrogen, halogen-c83218c83318324；C₁₋₄ haloalkyl,y -OR¹⁴；R2 and R3 were selected from hydrogen, halogen CN and r8310, respectively；R8311th,Or rim and rimTogether with the carbon atoms connected to them, they form a benzene ring or a pyridine ring, where the benzene ring is selectively replaced by one to four independent halogen substitutes.R8311th,And the pyridine ring is replaced by one or three independent halogen substitutes - CN, r8310,-R8311；R830808 has formula (2),Where a wavy line represents a connection point, from - or--C83228O--y -N (R) -R8308； (74919) selected from - ch8322r83099 and etenil and replaced by one to three independent halogenation, cyanogen and r8311811 alternatives；and (a) R⁴ᶜ is hydrogen, R⁴ᵉ is selected from hydrogen and C₁₋₄ alkyl when L is -N (R⁴ᵉ) -,R8308；； 7495y and r8308；； 74966；With the addition of nitrogen and carbon atoms, the content of r8308； 74955；R⁴ᶜ,and R⁴ᵈ are respectively attached, form a pyrrolidine ring or a piperidine ring, each ring optionally substituted with one to six substituents independently selected from halo, C₁₋₄ alkyl, and C₁₋₄ haloalkyl；or (b) R⁴ᵇ is selected from hydrogen and C₁₋₄ alkyl,R8308；]R8308； (75808 and r8308； (74977)；Together with a carbon atom and a nitrogen atom, r8308；； 758080,R⁴ᵈ,and R⁴ᵉ are respectively attached, form a pyrrolidine ring or a piperidine ring, each ring optionally substituted with one to six substituents independently selected from halo, C₁₋₄ alkyl,a. Halogenated tar c831832421；O (c) r8308； 7496es hydrogen, r8308； 74977 when l es-n (r8308； 7497) -,R8308；； 7495y and r8308；； 758080；together with the nitrogen and carbon atoms to which R⁴ᵇ and R⁴ᶜ are respectively attached, they form
