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섬유충진 입체형 지지체 및 그의 제조방법
专利权人:
KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY
发明人:
KO, Jae Hoon,고재훈,LEE, Hee Dong,이희동,IM, Jung Nam,임정남,PARK, Suk Hee,박석희,KIM, Tae Hee,김태희
申请号:
KRKR2017/014114
公开号:
WO2018/105980A1
申请日:
2017.12.05
申请国别(地区):
WO
年份:
2018
代理人:
摘要:
The present invention relates to a fiber-filled three-dimensional support and a manufacturing method therefor. The fiber-filled three-dimensional support of the present invention is advantageous for use as a tissue culture support for cell culture, proliferation, and differentiation, since a 3D printing structure formed of an in vivo absorbent polymer material is used as a frame and microfilaments formed of in vivo absorbent polymer material are filled in the three-dimensional direction inside the structure to achieve complexation, so that a pore size is properly controlled depending on a use of the support, a space sufficient for cell proliferation is provided, and an intercellular space interconnection is improved, thereby allowing three-dimensional cell proliferation.La présente invention concerne un support tridimensionnel rempli de fibres et son procédé de fabrication. Le support tridimensionnel rempli de fibres de la présente invention est avantageux pour utilisation en tant que support de culture de tissu pour la culture, la prolifération et la différenciation de cellules, étant donné quune structure dimpression 3D formée dun matériau polymère absorbant in vivo est utilisée en tant que cadre et des microfilaments formés dun matériau polymère absorbant in vivo sont remplis dans la direction tridimensionnelle à lintérieur de la structure pour obtenir une complexation, de sorte quune taille de pore soit correctement régulée en fonction de lutilisation du support, un espace suffisant pour la prolifération cellulaire est fourni, et une interconnexion despace intercellulaire est améliorée, de façon à permettre une prolifération cellulaire tridimensionnelle.본 발명은 섬유충진 입체형 지지체 및 그의 제조방법에 관한 것이다. 본 발명의 섬유충진 입체형 지지체는 생체내 흡수성 고분자 소재로 이루어진 3D 프린팅 구조체를 골격으로 하고 상기 구조체 내부에 생체내 흡수성 고분자 소재로 이루어진 마이크로 필라멘트사를 3차원 방향으로 충진하여 복합화함으로써 지지체 용도에 따라 적합한 공극크기를 제어하고, 세포증식에 충분한 공간을 제공하는 동시에 세포간 공간 연결성(interconnection)을 향상시켜 3차원으로 세포증식이 가능하도록 하여, 세포배양, 증식 분화시키는 조직배양지지체 용도에 유리하다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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