1. A system for multiphase release of growth factors in a treatment area, comprising: a) a delivery medium containing at least one growth factor, wherein the delivery medium is adapted to release at least one first growth factor with an initial delayed release profile for a first time period , and b) a carrier containing a plurality of particles having at least one second growth factor on its surfaces, the carrier being adapted to release at least one second growth factor over the course of a second time period, wherein the second time period has a longer duration than the first period of time, wherein the carrier comprises particles kaltsiya.2 sulfate dihydrate. The system of claim 1, wherein the carrier further comprises calcium phosphate particles. The system of claim 2, wherein the particle ratio of calcium sulfate dihydrate to calcium phosphate is from about 0: 1 to about 1: 0.4. The system of claim 1, wherein the delivery medium comprises a polymer. The system of claim 4, wherein the polymer is poloxamer 407.6. The system of claim 4, wherein the carrier particles are dispersed in the delivery medium. The system of claim 1, wherein the first time period includes hours or days. The system of claim 1, wherein the second time period includes days or weeks. The system of claim 1, wherein the carrier releases at least one second growth factor with a sustained release profile for a second period of time. The system of claim 1, wherein at least one first growth factor and at least one second growth factor are the same. The system of claim 10, wherein the growth factor is a bone morphogenetic protein-2, BMP-2.12. The system of claim 11, wherein the environment is accessible.1. Система для многофазного высвобождения факторов роста в зоне лечения, включающая:a) среду доставки, содержащую по меньшей мере один фактор роста, где среда доставки адаптирована для высвобождения по меньшей мере одного первого фактора роста с начальным профилем замедленного высвобождения в течени
