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SYSTEM AND METHOD FOR MULTIPHASIC RELEASE OF GROWTH FACTORS
专利权人:
INDUCE BIOLOGICS; INC.
发明人:
Sean A. F. Peel,Cameron M. L. Clokie
申请号:
US14509840
公开号:
US20150196620A1
申请日:
2014.10.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A system for multiphasic delivery of at least one growth factor at a treatment site comprises a delivery vehicle for releasing at least one growth factor in an initial release profile and a carrier for releasing at least one growth factor in a sustained release profile. The initial release profile releases at least one growth factor over a period of hours to days, wherein the growth factor is released in a large amount initially, with the remainder being released in progressively lower amounts. The sustained release profile releases at least one growth factor over a period of days to weeks, wherein the growth factor is released at a generally constant amount over such period. The system of the invention is particularly suited for applications on bioimplants. The invention also comprises methods and kits for multiphasic delivery of at least one growth factor. The invention also comprises calcium sulphate as a carrier for releasing at least one growth factor in both single and multiphasic systems for delivering at least one growth factor at a treatment site.
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中国工程科技知识中心
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