A respiratory mask, preferably a nasal mask, comprising a main body (1) comprising a holding arm (6) projecting upwardly from said main body (1) and two lateral arms (4, 5) projecting laterally from said main body (1), said two lateral arms (4, 5) and holding arm (6) being integrally fixed to said main body (1), and a tubular-shape portion (2) traversed by a central passage (3) and a flexible cushion (10) comprising a tubular structure (11a, 11b, 11c) traversed by a gas passage (11), said tubular structure (11a, 11b, 11c) cooperating with the tubular-shape portion (2) of the main body (1) so as to maintain the flexible cushion (10) coupled to the tubular-shape portion (2) of the main body (1). Further, the main body (1) comprises at least one lodging (7) and the flexible cushion (10) comprises at least one protruding element (13) projecting away, i.e. outwardly, from the external surface of the cushion (10), said protruding element (13) being at least partially inserted into the lodging (7) of the main body (1) when the flexible cushion (10) is coupled to the main body (1). The respiratory mask of the present invention is useable for treatment of a respiratory disorder or condition in non-invasive positive pressure ventilation or in a nasal continuous positive airway pressure therapy of sleep disordered breathing conditions, such as obstructive sleep apnea.