DEREK VAN LONKHUYZEN,GARY KEITH SHOOTER,JESSE PEET,SIMONE RIZZI,TRISTAN CROLL,ZEE UPTON
申请号:
BRPI1009325
公开号:
BRPI1009325A2
申请日:
2010.03.19
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Methods of screening or designing therapeutic agents effective for the treatment of a transglutaminase-associated disease, disorder and/or condition are provided which include determining whether a candidate agent can modulate an interaction between a transglutaminase and an insulin-like growth factor and/or a member of the IGF family of receptors. Also provided are pharmaceutical compositions and methods of treatment using said pharmaceutical compositions.