VASIEVICH, ELIZABETH ANN,CHEN, WEIHSU,TONEY, KENYA,CONN, GREGORY,BEDU-ADDO, FRANK,HUANG, LEAF
申请号：
CA2721366
公开号：
CA2721366C
申请日:
2009.04.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A composition and method for activating immune cells ex-vivo, or inducing animmune response in a subject includinga composition comprising at least one chiral cationic lipid. The chiralcationic lipid in one embodiment comprises a nonsteroidalcationic lipid having a structure represented by formula (I) wherein in R1 isa quaternary ammonium group, Y1 is a spacerchosen from a hydrocarbon chain, an ester, a ketone, and a peptide, C* is achiral carbon, R1 and R3 are independently chosenfrom a saturated fatty acid, an unsaturated fatty acid, an ester-linkedhydrocarbon, phosphor-diesters, and combinations thereof.
