Methods of modulating T cell-mediated immune responses with anti-P-selectin glycoprotein ligand 1 antibodies

• 收藏
• 分享

专利权人:

Rong-Hwa Lin;Chung-Hsiun Wu;Pei-Ling Hsu

发明人:

Rong-Hwa Lin,Chung-Hsiun Wu,Pei-Ling Hsu

申请号：

US12494018

公开号：

US08298540B2

申请日:

2009.06.29

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Compounds that bind to P-Selectin Glycoprotein 1 (PSGL-1) on the surface of T cells or natural killer (NK) cells can be used to induce T cell or NK cell depletion and/or to induce T cell or NK cell apoptosis. The compounds and methods of the invention can be used to control unwanted T cell- or NK cell-mediated immune responses in conditions such as autoimmune diseases, transplant rejection, and allergic diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/