INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA (INIA);CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC);UNIVERSITAT POMPEU FABRA
发明人:
申请号：
EP07803672.0
公开号：
EP2053056B1
申请日:
2007.08.01
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
This construct is one of formula (I) wherein: T is a peptide comprising the sequence SEQ ID NO: 1 or a fragment thereof； B is a peptide comprising the sequence SEQ ID NO: 2 or a fragment thereof； X is an acyl group bound to the N-terminal end of B； n is 3 or 4； and L corresponds to a lysine core of formula (II) where W is a linker； Z 1 -Z 4 are equal or different to each other and are selected from the group consisting of cysteine and-OH, provided that at least three of the groups Z 1 to Z 4 are cysteine； the peptide B being linked to the lysine core by its C-terminal end and the peptide T being linked to said lysine core by its N-terminal end. €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ(X-B)n-L-T€ƒ€ƒ€ƒ€ƒ€ƒ(I)
