Jakobovits, Aya,Raitano, Arthur B.,Faris, Mary,Hubert, Rene S.,Ge, Wangmao,Morrison, Karen Jane Meyrick,Morrison, Robert Kendall,Challita-Eid, Pia M.
申请号:
AU2010226920
公开号:
AU2010226920B2
申请日:
2010.10.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2010226920B220120119.pdf#####ABSTRACT A novel gene 0161P2FIOB (also designated 161P2FIOB) and its encoded protein, and variants thereof, are described wherein 161P2FIOB exhibits tissue specific 5 expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2FOB provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161 P2F I OB gene of fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F1OB 10 can be used in active or passive immunization.