MARY FARIS,RENE S. HUBERT,WANGMAO GE,AYA JAKOBOVITS,PIA M. CHALLITA-EID,ARTHUR B. RAITANO,KAREN JANE MEYRICK MORRISON
申请号:
PT02797088
公开号:
PT1537140E
申请日:
2002.11.07
申请国别(地区):
PT
年份:
2013
代理人:
摘要:
A gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene of fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.