A lower extremity wound information system can include a lower extremity wound treatment monitoring device and an external wound care information system. The monitoring device can include a moisture sensor placed at an external surface of a primary wound dressing. The moisture sensor generally would not be placed in direct contact with the wound. The monitoring device can also include a base unit placed on a posterior calf of the patient. The base unit can include a second sensor, a controller, and a communication module. The controller can receive and process information from the sensors, and determine whether to communicate information relating to the information from the sensors via the communication module to an external recipient. The external wound care information system can receive the information relating to the information from the sensors, and if appropriate, can prompt scheduling of a dressing change appointment for the patient.