FARMER LUC J,FOURNIER PIERRE ANDRE,LE SSARD STEPHANIE,LIU BINGCAN,ST ONGE MIGUEL,STURINO CLAUDIO,SZYCHOWS KI JANEK,YANNOPOULOS CONSTANTIN,VALLEE FREDERIC,LACOSTE JEAN E RIC,MARTEL JULIEN,BUBE NIK MONI
申请号：
IN201637010580
公开号：
IN201637010580A
申请日:
2016.03.28
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to compounds useful as inhibitors of the PAR-2 signaling pathway. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and methods of using the compounds in in vitro applications, such as the study of GPCRs in biological and pathological phenomena； the study of intracellular signal transduction pathways mediated by such GPCRs； and the comparative evaluation of new inhibitors of the PAR-2 signaling pathway. The compounds of this invention have formula I: wherein the variables are as defined herein.
