Disclosed is a multiple unit tablet composition comprising enteric coated multiple unit cores comprising esomeprazole, wherein plasticizer content of the enteric coating is less than about 10% by weight of the enteric coating polymer； at least two diluents and optionally one or more other pharmaceutically acceptable excipient, wherein one diluent is microcrystalline cellulose with rodform particles. Also disclosed is a process for preparing the tablet composition.
