O'MAHONY, GAVIN,KOSSENJANS, MICHAEL,EDMAN, KARL,KAJANUS, JOHAN,HOGNER, CARL ANDERS,CORNWALL, PHILIP,TURNER, ANDREW,OMAHONY, GAVIN
申请号:
CA2953655
公开号:
CA2953655A1
申请日:
2015.06.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed arecertain derivatives of benzoxazinone amidesof formula (I),or pharmaceutically acceptable salts thereof, (Formula (I)) that act as mineralocorticoid (MR) receptor modulatorsthat may reduce oxidative stress in endothelium and hence improve vascular function, to methods for their potential therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.