UNIVERSITY OF MARYLAND, BALTIMORE;UNIVERSITY OF MARYLAND EASTERN SHORE;UNIVERSITY OF MARYLAND; BALTIMORE;THOMAS JEFFERSON UNIVERSITY
发明人:
NJAR, VINCENT C.O.,GEDIYA, LALJI K.,PURUSHOTTAMACHAR, PURANIK,GODBOLE, ABHIJIT,KWEGYIR-AFFUL, ANDREW,VASAITIS, TADAS
申请号：
CA2904170
公开号：
CA2904170A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant. The compounds are potential agents for the treatment of all forms of prostate cancer and other diseases that depend on functional AR.
