HIGHLY PURE ELETRIPTAN OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUBSTANTIALLY FREE OF ELETRIPTAN N-OXIDE IMPURITY

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专利权人:

发明人:

VIJAYA GOPAL KUSUMBA,SAMPATH KUMAR SANKINENI,NEELA PRAVEEN KUMAR,NITIN SHARADCHANDRA PRADHAN

申请号：

IN411/CHE/2009

公开号：

IN2009CH00411A

申请日:

2009.02.25

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

Provided herein is an impurity of eletriptan, eletriptan N-oxide, (R)-5-[2-(phenylsulfonyl)ethyl]-3-[(l-methyl-2-pyrrolidinyl-N-oxide)methyl]-lH-indole, and a process for the preparation and isolation thereof. Provided further herein is a highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan N-oxide impurity, processes for the preparation thereof, and pharmaceutical compositions comprising highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan N-oxide impurity.

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