Constrained tricyclic sulfonamides

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专利权人:

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

发明人:

Michael Ohlmeyer,David Kastrinsky

申请号：

US15124888

公开号：

US09937180B2

申请日:

2015.03.10

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Tricyclic chemical modulators of protein phosphatase 2A are disclosed. The compounds are useful to treat cancer, age-onset proteotoxicity, stress-induced depression, inflammation, and acne. The compounds are of the following phenothiazine and dibenzoazepine compounds and similar genera:

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