PROBLEM TO BE SOLVED: To provide a material which solves the problems in the conventional temperature-responsive sol gel transition polymer, exhibits temperature-responsive sol gel transition under a low concentration condition and further has protein inclusion and sustained-release property, cell inclusion property and cell adhesiveness in a gel state.SOLUTION: There is obtained a composite material by mixing an aqueous solution of a temperature-responsive polymer having water solubility and biodegradability and an aqueous solution of a clay mineral having a nanosheet structure. The temperature-responsive polymer preferably is an ABA-type triblock copolymer having a hydrophobic block A and a hydrophilic block B.COPYRIGHT: (C)2015,JPO&INPIT【課題】本発明の課題は、従来の温度応答性ゾル‐ゲル転移ポリマーにおける問題を克服し、低濃度条件で温度応答性ゾル‐ゲル転移を示し、さらにゲル状態でタンパク質内包・徐放性、細胞内包性、細胞接着性を特徴とする材料を提供することにある。【解決手段】水溶性かつ生分解性を有する温度応答性ポリマーの水溶液と、ナノシート構造を有する粘土鉱物の水溶液とを混合し、複合材料を得る。温度応答性ポリマーは、疎水性ブロックAと親水性ブロックBとを有するABA型トリブロック共重合体であることが好ましい。【選択図】なし
