Daniel M. Schwartz,Scott Fraser,Robert H. Grubbs,Justin P. Gallivan,Changjun Yu
申请号:
US12126100
公开号:
US08298521B2
申请日:
2008.05.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruchs membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruchs membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.