Referring to a Heterocyclic Compound of formula (i), where n is 0, 1 or 2 C1 - C6 r1 is alkyl, cycloalkyl C3 C6, among others R2 is H, c1-c4 alkyl c1-c4 alkyl, - C (o) R3 and R4 with the carbon Atom at We are United to form a group cicloalquileno C3 C6 optionally replaced with a r Further R3.1 where a CH2 Group can be replaced by a heteroatom o, N, S, or a Group Co, so or SO2 R3.1 is H or Oh R5 is H, c1-c4 alkyl, among others R6 h, halogen, CN, o, among others R7 is H, halogen, alkyl of C1 - C6, among others R8 is H, halogen, c1-c4 alkyl R9 is H, halogen, NS, Oh, c1-c6 alkyl, among others, R10 is H, halogen, c1-c4 alkyl R11 is H, halogen, alkyl of C1 CN, o - C6, among others.Preferred compounds are: 4 - (2 - trifluoromethyl - acid bencilamida phenylamino) - 1 - (2 - methoxy - Acetylamino) - ciclopropanocarboxilico, {1 - [4 - (2 - trifluoromethyl - phenylamino) - bencilcarbamoil] - cyclopropyl amide acid} - 1 - methyl - 4 - 1H imidazole carboxylic acid, N - [1 - [4 - (2 - trifluoromethyl - phenylamino) - bencilcarbamo Il - cyclopropyl}] - benzamide, among others. It also relates to a Pharmaceutical composition.These compounds have antagonist activity on bradykinin B1 Receptors and are useful in the treatment of acute pain, such as Pain, visceral Pain, inflammatory Pain, among othersREFERIDA A UN COMPUESTO HETEROCICLICO DE FORMULA (I), DONDE n ES 0, 1 O 2 R1 ES ALQUILO C1-C6, CICLOALQUILO C3-C6, ENTRE OTROS R2 ES H, ALQUILO C1-C4, ALQUIL C1-C4-C(O) R3 Y R4 JUNTO CON EL ATOMO DE CARBONO A QUE ESTAN UNIDOS FORMAN UN GRUPO CICLOALQUILENO C3-C6 OPCIONALMENTE SUSTITUIDO CON UN RADICAL R3.1 DONDE UN GRUPO CH2 PUEDE ESTAR REEMPLAZADO POR UN HETEROATOMO O, N, S O UN GRUPO CO, SO O SO2 R3.1 ES H U OH R5 ES H, ALQUILO C1-C4, ENTRE OTROS R6 ES H, HALOGENO, CN, OH, ENTRE OTROS R7 ES H, HALOGENO, ALQUILO C1-C6, ENTRE OTROS R8 ES H, HALOGENO, ALQUILO C1-C4 R9 ES H, HALOGENO, CN, OH, ALQUILO C1-C6, ENTRE OTROS R10 ES H, HALOGENO, ALQUILO C1-C4 R11 ES H, HALOGENO, CN, OH, ALQUILO C1-
