Seung Bum Park,Bong Rae Cho,Hyang Yeon Lee,Jong Min Park
申请号:
US12876367
公开号:
US08632749B2
申请日:
2010.09.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed herein are compounds useful as two-photon tracers. Also, methods are provided for visualizing intracellular glucose uptake, screening anticancer agents, and diagnosing cancer using the compounds. They exhibit preferential uptake by cancer cells, penetrability sufficient to allow bright section images, high water solubility, high pH resistance and low toxicity in addition to applicability to living cells in deep tissues over a long period of time.