A medical system may include an insertion device having a handle, a shaft coupled to the handle of the insertion device, and a port positioned on the handle of the insertion device. The port may be in fluid communication with a working channel of the shaft. The port may be a female luer port. The medical system may further include a medical device having a control member terminating in an end effector, a handle having a plurality of circumferential slots along the length of the handle, and a plunger moveable along a longitudinal axis of the handle of the medical device between a first position and a second position. In the first position, the end effector may be positioned within the shaft, and in the second position, the end effector may be positioned distally of the shaft.