KIM, NAM HO,LEE, JIN YOUNG,KIM, JAE-SUN,LEE, NAM KYU,JANG, WOO JAE,OH, JOON GYO,LEE, YOON-JUNG,KIM, WOONG SIK,SUNG, JIN-HEUNG,UM, KEY AN
申请号:
EP07746627
公开号:
EP2019664A4
申请日:
2007.05.22
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.