Petrus Johannes Lenting,Jan Aart Van Mourik,Koenraad Mertens,Hans Pannekoek,Peter Turecek,Hans-Peter Schwarz,Friedrich Scheiflinger
申请号：
US12388665
公开号：
US08546332B2
申请日:
2009.02.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
