Byeong Woo Park;Donald M. O'Rourke;Mark I. Greene;Ramachandran Murali
发明人:
Mark I. Greene,Donald M. O'Rourke,Ramachandran Murali,Byeong Woo Park,Donald M. ORourke
申请号：
US14485525
公开号：
US20150010551A1
申请日:
2014.09.12
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Methods of treating an individual who has an erbB protein mediated tumor is disclosed. Methods of preventing erbB protein mediated tumors in an individual are disclosed. The methods comprise administering to the individual a nucleic acid molecule that encodes a protein that dimerizes with an erbB protein and that is deficient in tyrosine kinase activity. Composition that comprise such nucleic acid molecules including pharmaceutical compositions are disclosed.
