Mark I. GREENE,Donald M. O'ROURKE,Ramachandran MURALI,Byeong Woo PARK,Donald M. OROURKE
申请号:
US15422046
公开号:
US20170355778A1
申请日:
2017.02.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Methods of treating an individual who has an erbB protein mediated tumor is disclosed. Methods of preventing erbB protein mediated tumors in an individual are disclosed. The methods comprise administering to the individual a nucleic acid molecule that encodes a protein that dimerizes with an erbB protein and that is deficient in tyrosine kinase activity. Composition that comprise such nucleic acid molecules including pharmaceutical compositions are disclosed.