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Medical devices and methods for modulation of physiology using device-based surface chemistry
专利权人:
Bruce N. Saffran
发明人:
Bruce N. Saffran
申请号:
US11052204
公开号:
US09050393B2
申请日:
2005.02.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention provides implantable medical devices having at least one moiety attached to the surface capable of catalyzing a reaction in vivo. The implantable medical device has a body such as a stent with a surface adapted to be placed adjacent to a biological tissue or fluid. The body has at least one moiety attached to the surface which is capable of catalyzing a first reaction upon contacting a first substrate in the biological tissue or fluid. The moiety remains attached to the surface after the first reaction and is capable of catalyzing at least a second reaction upon contacting a second substrate. In preferred embodiments the moiety is capable of catalyzing a multitude of reactions as substrates come into contact and then leave the surface of the device.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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