An endobronchial ultrasound (EBUS) bronchoscope is configured as a single-use (e.g., disposable) device. The bronchoscope includes an insertion tube having a proximal section adjacent the handle and a distal tip. An ultrasound transducer assembly is located at the distal tip. The ultrasound transducer assembly includes an ultrasound transducer array, transmit-and-receive circuitry for the ultrasound transducer array, and a flexible interconnection between the ultrasound transducer array and the transmit-and-receive circuitry. The insertion tube further includes an imaging lumen including one or more power cables and one or more communication wires that extend from the ultrasound transducer assembly through the proximal section and a working channel that is separate from the imaging lumen.
