A method for determining brain state has the steps of attaching at least 2 first electrodes to the scalp of a subject at a separation, transmitting an electrical current between the at least 2 first electrodes, and measuring a first impedance between the at least 2 first electrodes to provide a resulting impedance. One embodiment has the further step of comparing the resulting impedance to pre-stored impedance measurements of the scalp to determine normal or pathological state. A further embodiment has the steps of attaching 2 first electrodes to the scalp of a subject at a separation and 2 second electrodes, transmitting a current between the first electrodes and measuring a first impedance between the second electrodes to provide a resulting impedance. The electrodes may be driven shield electrodes, and the method may further include comparing impedance measurements to pre-stored impedance measurements to determine normal and pathological state.