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PHOTOACOUSTIC CONTRAST AGENT HAVING LIPID PARTICLE CONTAINING SILICON NAPHTHALOCYANINE ANALOG
专利权人:
发明人:
Fumiko Tomatsu,Tatsuki Fukui,Daisuke Sasaguri,Mayuko Kishi,Kouichi Kato,Satoshi Yuasa
申请号:
US14300433
公开号:
US20140377180A1
申请日:
2014.06.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A conventional silicon naphthalocyanine-containing liposome is required to incorporate a dye dispersed therein for use in photodynamic therapy, and is thus low in dye content and also low in photoacoustic signal. According to a lipid particle containing a silicon naphthalocyanine analog, in which the ratio A/B of an absorption coefficient A at a first absorption local maximum to an absorption coefficient B at a second absorption local maximum in a range from 700 nm to 800 nm is 5.0 or less, the dye content in the lipid particle can be increased and the photoacoustic signal intensity can be improved.
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中国工程科技知识中心
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