A device for treatment of valve regurgitation is described, comprising frameworks (114, 133, 141, 701, 812, 821, 911) and an anchoring unit (132). The anchoring unit (132) is connected to the frameworks (114, 133, 141, 701, 812, 821, 911)； the frameworks (114, 133, 141, 701, 812, 821, 911) can be expanded and compressed and have an inflow end (421) and an opposite outflow end (422)； valve leaflets (142, 621, 721, 751) capable of opening and closing in blood flow are provided inside the frameworks (114, 133, 141, 701, 812, 821, 911)； the anchoring unit (132) can keep the frameworks (114, 133, 141, 701, 812, 821, 911) in an expanded state at the orifice position of a natural heart valve. The device for treatment of valve regurgitation and an implantation method therefor can effectively treat valve regurgitation.
