MARTINEZ BOTELLA, GABRIEL,SALITURO, FRANCESCO G.,ROBICHAUD, ALBERT JEAN,HARRISON, BOYD L.
申请号:
CA2964766
公开号:
CA2964766A1
申请日:
2015.10.16
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein (II), A, R1, R2, R3a, R4a, R4b, R5, R7a, and R7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.