MARTINEZ BOTELLA, GABRIEL,SALITURO, FRANCESCO G.,ROBICHAUD, ALBERT JEAN,HARRISON, BOYD L.
申请号:
CA2964898
公开号:
CA2964898A1
申请日:
2015.10.16
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein, R1, R2a, R2b, R3and A are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.