Xuemei Peng;Ramulu Poddutoori;Edward Roberts;Hugh Rosen;Miguel A. Guerrero;Steven Brown
发明人:
Edward Roberts,Hugh Rosen,Steven Brown,Miguel A. Guerrero,Xuemei Peng,Ramulu Poddutoori
申请号:
US13605561
公开号:
US08481573B2
申请日:
2012.09.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds of the following generic structure are provided:Such compounds activate a sphingosine-I-phosphate receptor of the subtype 1 (S1P1), and have utility in the treatment of malconditions mediated by S1P1 activation. More specifically, such compounds are beneficial in the treatment of, for example, multiple sclerosis, transplant rejection and/or adult respiratory syndrome.