Xuemei Peng;Ramulu Poddutoori;Edward Roberts;Hugh Rosen;Miguel A. Guerrero;Steven Brown
发明人:
Edward Roberts,Hugh Rosen,Steven Brown,Miguel A. Guerrero,Xuemei Peng,Ramulu Poddutoori
申请号:
US12465767
公开号:
US08796318B2
申请日:
2009.05.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.