INHIBITEURS A PETITES MOLECULES DE PHOSPHORYLATION DE PROMOTEUR DE MORT ASSOCIE A BCL-2 (BAD)

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专利权人:

UNIVERSITY OF MYSORE;BANGALORE UNIVERSITY;NATIONAL UNIVERSITY OF SINGAPORE

发明人:

LOBIE, PETER EDWARD,PANDEY, VIJAY KUMAR,KANCHUGARAKOPPAL SUBBEGOWDA, RANGAPPA,SALUNDI, BASSAPPA,CHAKRABHAVI DHANANJAYA, MOHAN,RANGAPPA, SHOBITH,VENKATACHALAIAH, SRINIVASA

申请号：

CA3060939

公开号：

CA3060939A1

申请日:

2018.04.18

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The invention relates to compounds of general formula (I): wherein R1,n,R2a,R2band R3 are as defined herein. The compounds are inhibitors of Bc1-2-associateddeath promoter (BAD)phosphorylation and have anti-apoptotic activity and are useful in thetreatment of cancer, particularlybreast cancer, endometrial cancer, ovarian cancer, liver cancer, colon cancer,prostate cancer or pancreaticcancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/