KUSUMI, Kensuke,KURATA, Haruto,NAGANAWA, Atsushi,KODERA, Yasuyo,INAGAKI, Yuichi,TAKIZAWA, Hiroya,WOLF, Mark Allan,RAKER, Joseph
申请号:
EP15865945
公开号:
EP3228615A4
申请日:
2015.12.03
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
A compound shown by general formula (I) (in the formula, all of the symbols are as defined in the specification) has selective S1P5 receptor agonist activity due to having a linker from a phenyl group to a cyclic substituent in a dihydronaphthalene skeleton i.e., due to having a short linker of one atom or less as L in general formula (I), and can therefore serve as an agent for the treatment of S1P5-mediated diseases, e.g., neurodegenerative diseases such as schizophrenia.