Kensuke KUSUMI,Haruto KURATA,Atsushi NAGANAWA,Yasuyo KODERA,Yuichi INAGAKI,Hiroya TAKIZAWA,Mark Allan WOLF,Joseph RAKER
申请号:
US15532389
公开号:
US20170327439A1
申请日:
2014.12.03
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A compound represented by general formula (I)(wherein, all the symbols are as defined in the specification) has a selective S1P5 receptor agonist activity due to having a linker from a phenyl group to a cyclic substituent in a dihydronaphthalene skeleton; .i.e., due to having a short linker of one atom or less as L in general formula (I), and can therefore serve as an agent for treating S1P5-mediated disease, e.g., neurodegenerative disease such as schizophrenia.