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含羅替戈汀之貼附劑
专利权人:
HISAMITSU PHARMACEUTICAL CO.; INC.
发明人:
ARAKI, HIROYUKI,荒木浩行,TAKAGI, YUKA,高木佑香,高木祐香,FUJIWARA, YOKO,藤原遥子,KOBAYASHI, HIROAKI,小林弘明,KUROKAWA, TAKAO,黒川隆夫
申请号:
TW107145836
公开号:
TW201927291A
申请日:
2018.12.19
申请国别(地区):
TW
年份:
2019
代理人:
摘要:
Provided is a Rotigotine-containing patch having a support layer and an adhesive layer, wherein the adhesive layer contains Rotigotine and/or a pharmaceutically acceptable salt thereof, and further contains a styrene-based thermoplastic elastomer, a petroleum-based resin and/or a terpene-based resin, an aliphatic alcohol, and a crosslinked polyvinyl pyrrolidone. In the adhesive layer, the mass ratio of the content of Rotigotine and/or the pharmaceutically acceptable salt as converted to a Rotigotine free form to the content of the crosslinked polyvinyl pyrrolidone (i.e., the content of Rotigotine and/or the pharmaceutically acceptable salt as converted to a Rotigotine free form : the content of the crosslinked polyvinyl pyrrolidone) is 10:3-1:3.本發明係一種含羅替戈汀之貼附劑,其特徵在於:其係具備支持體層及黏著劑層,且上述黏著劑層含有羅替戈汀及/或其藥學上容許之鹽者,且上述黏著劑層進而含有苯乙烯系熱塑性彈性體、石油系樹脂及/或萜烯系樹脂、脂肪族醇、及交聯聚乙烯基吡咯啶酮,且於上述黏著劑層中,羅替戈汀及/或其藥學上容許之鹽之換算為羅替戈汀游離體之含量與交聯聚乙烯基吡咯啶酮之含量之質量比(羅替戈汀及/或其藥學上容許之鹽之羅替戈汀游離體換算含量:交聯聚乙烯基吡咯啶酮含量)為10:3~1:3。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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