The invention relates to a surface treatment method for dental implants with tissue integration.It is treated by sandblast, large grid, acid etched, SLA.The surface roughness of titanium metal is different.The surface of the titanium metal was cleaned and embedded with TTCP.The bone mother cells (MC3T3-E1) that will be contacted after implantation were used.Fibroblasts (NIH3T3) and epidermal cells (xb-2) were cultured.By looking for the surface conditions suitable for the growth and attachment of the above cells,Different surface treatments were used to balance the osteoblasts between the oral tissue and the implant.The growth rate of fibroblasts and epidermal cells.In order to increase the success rate of implant implantation,At the same time, it provides calcium for the growth of the osteoblast.Accelerating the growth of the osteoblast and inhibiting the growth rate of the fibroblast.一種具組織整合之齒科植體表面處理方法，係利用表面噴砂及酸蝕(Sandblasted,Large-grit,Acid-etched,SLA)處理方式，使鈦金屬表面產生不同之粗糙度(Roughness)，且使用磷酸鈣鹽系列之四鈣磷酸鹽(Tetracalcium Phosphate,TTCP)以二次噴砂方式對該鈦金屬表面進行清潔及嵌入，並以植體植入後會接觸之骨母細胞(MC3T3-E1)、纖維母細胞(NIH 3T3)及表皮細胞(XB-2)進行培養，經由尋找適合上述各細胞生長及貼附之表面狀況，利用不同之表面處理調整平衡口腔組織與植體之間骨母細胞、纖維母細胞及表皮細胞之生長速度，俾以達到增加植體植入後之成功率，同時提供該骨母細胞生長所需之鈣離子，加速該骨母細胞並達到抑制該纖維母細胞之生長速率者。
