The purpose of the present invention is to provide a controlled release formulation which can both prevent a compound A from being released precipitously and release the compound A in a pH-independent manner and contains 2-{4-[N-(5,6-diphenylpyradine-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide as an active ingredient. The controlled release formulation is characterized by containing 2-{4-[N-(5,6-diphenylpyradine-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide, a water-soluble polymer, a functionalized starch, and an alkali substance, and having a pH of 10 or more.
