Jeffrey Colledge,Thomas Alfred Profitlich,Ulrich Patzak,Taoufik Ouatas,Margaretha Olthoff
申请号：
US13132343
公开号：
US20120003309A1
申请日:
2009.12.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
In the present invention there is provided a pharmaceutical composition in a solid dosage form suitable for oral administration, the composition comprising bendamustine or a pharmaceutically acceptable ester, salt or solvate thereof as an active ingredient, and at least one pharmaceutically acceptable excipient, which is a pharmaceutically acceptable saccharide selected from the group consisting of one or more of a monosaccharide, a disaccharide, an oligosaccharide, a cyclic oligosaccharide, a polysaccharide and a saccharide alcohol, wherein the ratio by weight of the active ingredient to the saccharide excipient(s) is in the range of 1:1-5.
